Australasian Medical & Scientific Limited (AMSL) pride themselves in offering innovative solutions in regenerative medicine to positively impact the quality of patients’ lives. A search for a quality, established Platelet-Rich Plasma (PRP) system, which offers additional benefits for a seamless transition into your practice has lead them to introduce Cellenis® PRP.

What is PRP?

Platelet Rich Plasma (PRP) is an innovative and promising approach in tissue regeneration1. PRP is defined as an autologous concentrated preparation of platelets and their associated growth factors in a small volume of plasma1.

CELLENIS® advanced gel separation technology produces the optimal PRP. Before now, PRP systems were unable to sustain the mononuclear cell populations while eliminating red blood cells (RBC) and neutrophils. Cellenis® gel separation removes cells that promote inflammation and catabolism while producing a solution rich in platelets and monocytes which optimise healing and growth.

Monocyte-rich, Neutrophil-poor PRP

In the presence of monocytes, platelets release growth factors and anabolic cytokines. PRP rich in monocytes can enhance the healing and growth process.

In the presence of granulocytes, platelets will release catabolic cytokines. Therefore, PRP rich in neutrophils can inhibit the healing and growth process.

How does Cellenis® PRP work?

A small sample of blood is taken from the patient’s arm. The blood is centrifuged, and 10 minutes later, the PRP separates from the whole blood and is ready to use.

Once on site, the growth factors and other regenerative molecules are released leading to collagen and elastin formation as well as cellular growth and skin remodelling. This may result in skin rejuvenation and a reduction in wrinkles and scars2.

What is the Therapeutic effect of PRP?

PRP is thought to promote physiological wound healing and rapid tissue regeneration by delivering growth factors at high concentrations to the treated site2.

What are the benefits of Cellenis®PRP?

This treatment may improve skin texture and tone, refines wrinkles and reduces scars such as acne or stretch marks while preserving a natural appearance2. Cellenis PRP can also be used to promote hair growth when injected into the scalp.

Visible results may take between 2-6 weeks and will vary between individuals. This variance depends on factors such as general health, age, diet, smoking and skin type3.

Unique Features and Benefits of Cellenis® PRP:

  • 10-minute spin time
  • Physiologic pH anti-coagulant
  • Higher anabolic to catabolic cells ratio of 22:1
  • Monocytes out number neutrophils by 2.7:1
  • The separating gel is stable and maintains separation: eliminating RBC
  • Available in both 11 mL and 22 mL tubes
  • Flexibility to concentrate the dose of PRP further

Can this treatment be used in conjunction with other treatment?

Clinical evidence has shown that combining PRP with other rejuvenation techniques, such as fillers, mesotherapy and laser treatments, induces a synergistic beneficial effect2.

References:
1. Platelet-rich plasma: a review of biology and applications in plastic surgery. Eppley BL et al. Plast Reconstr Surg. 2006
2. Emer, J., 2019. Platelet-Rich Plasma (PRP): Current Applications In Dermatology. [online] Skin Therapy Letter. Available at: <http://www.skintherapyletter.com/dermatology/platelet-rich-plasma-prp/> [Accessed 28 July 2020].
3. Gupta, A., Versteeg, S., Rapaport, J., Hausauer, A., Shear, N. and Piguet, V., 2019. The Efficacy of Platelet-Rich Plasma in the Field of Hair Restoration and Facial Aesthetics—A Systematic Review and Meta-analysis. Journal of Cutaneous Medicine and Surgery, 23(2), pp.185-203. ICMS guidelines, section VIII

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