A newly published US study delivers the most comprehensive dataset to date on complication rates, risk factors and safety thresholds in accredited day surgery for aesthetic procedures.

A 29-year prospective study spanning 42,720 procedures at a single accredited facility has set a new benchmark for outpatient plastic surgery safety. The findings, recently published in the Journal of Plastic and Reconstructive Surgery, present robust data that are likely to influence perioperative protocols and patient triage decisions in cosmetic surgery worldwide.

Conducted at the Dallas Day Surgery Center, an AAAASF-accredited ambulatory facility in Texas, the study, led by Rachel N Rohrich BS and Tal Brown BS, and including prominent plastic surgeon Dr Rod J Rohrich, is now the largest single-site series in the literature on outpatient plastic surgery. The authors state, ‘To the authors’ knowledge, this is the largest long-term private practice plastic surgery study in accredited outpatient settings spanning almost 30 years.’

This comprehensive dataset provides clarity on the key variables influencing patient outcomes, including cut-offs for BMI, operative time and lipoaspirate volume that correlate with complication risk.

Study design & methodology

The prospective cohort encompassed every aesthetic surgery performed at the centre between 1995 and 2023. The patient cohort included individuals aged 18 and older undergoing procedures by board- certified plastic surgeons under general anaesthesia. A total of 42,720 consecutive cases were recorded. Data collected included patient demographics, procedure type, operative duration, body mass index (BMI), lipoaspirate volume, incidence of combined procedures, 30-day complication rates, return to operating room (ROR) and unplanned inpatient transfer.

Bivariate logistic regression was used to analyse associations between variables and adverse outcomes. Receiver-operator-characteristic (ROC) curve analysis was employed to determine specific thresholds for increased risk. The level of statistical significance was set at p < 0.05.

The operative profile reflected typical contemporary demand: 38 percent of cases were facial, 34 percent breast- related, and 28 percent percent body procedures. The median patient age was 46.4 years, with a mean BMI of 25.2 kg/m2. Average operative time was 3.1 hours.

Patients with a BMI over 25.96 kg/m2 or operative times exceeding three hours were more likely to experience complications. likewise, lipoaspirate volumes greater than 3 litres correlated with increased risk.

Study design at a glance

  • Setting: Dallas Day Surgery Center, AAAASF accredited
  • Period: 1995–2023 (29 years)
  • Surgeons: US board-certified plastic surgeons only
  • Sample: A total of 42,720 consecutive cases were performed.
  • Data captured: Demographics, procedure type, operative time, lipoaspirate volume, combined versus single procedures, 30-day complications, returns to theatre (ROR) and hospital transfers
  • Analysis: Bivariate logistic regressions with receiver- operator-characteristic cut-offs; significance set at P < 0.05

Overall safety profile

The results reinforce the safety of accredited outpatient surgery when conducted within established protocols by qualified teams. The overall complication rate was 0.74 percent (n = 318). There were 266 returns to theatre (ROR rate: 0.62 percent) and 43 unplanned hospital transfers (0.1 percent). Mortality was rare, with three deaths recorded over the 29-year period; an incidence of 0.007 percent.

Low complication rates, with clear inflection points

Despite a strong safety profile, the analysis revealed several key predictors of elevated risk. The most significant among these was undergoing combined procedures, defined as two or more surgical interventions performed in a single session.

Higher body mass index (BMI) and longer operative times were also found to be statistically significant. ‘Our analysis underscores the clear association between higher BMI and increased complications, particularly in the context of combined body procedures,’ the study states.

Patients with a BMI over 25.96 kg/m2 or operative times exceeding 3 hours were more likely to experience complications. Likewise, lipoaspirate volumes greater than 3 litres correlated with increased risk.

‘According to our findings, prolonged operative duration is significantly associated with a 1.32-fold increased risk of inpatient transfer and a 1.45-fold increased risk of VTEs,’ the authors note.

‘Operative time greater than 2.95 hours and 4.08 hours was identified as a risk factor for developing VTEs and inpatient transfer, respectively. Our subgroup analysis by procedure type corroborated these findings, demonstrating that operative duration carries similar risks, regardless of the procedure focus.’

Importantly, the study found no significant association between patient age and complication rates. ‘In our analysis… age did not emerge as a significant independent predictor for complications,’ said the authors.

The impact of combined procedures

The strongest predictor of adverse outcomes was combining multiple procedures in a single operative session. The authors state, ‘Undergoing a combined procedure was the strongest predictive factor for venous thromboembolism and inpatient admissions.’

This trend was particularly evident in abdominoplasty patients. Over half of all hospital transfers followed abdominoplasty, with 79 percent of those cases involving simultaneous liposuction. Combined abdominoplasty increased the odds of inpatient transfer by 3.73-fold and the odds of VTE by 12.65-fold.

Returns to theatre were also more common in combined procedures. The authors report, ‘The incidence of return to operating room was significantly increased in patients undergoing combined procedures (OR 3.40; p = 0.002).’

Breakdown by procedure type

Of the total procedures reviewed, face-related surgeries accounted for 38 percent, breast surgeries 34 percent and body procedures 28 percent. Face-related procedures had the lowest overall complication rate, while body surgeries, especially those involving abdominoplasty, showed the highest incidence of serious complications such as VTE.

The retrospective study found abdominoplasty cases comprised the bulk of serious complications, including VTEs and transfers. ‘Remarkably, 89 percent of all VTE incidents in the entire cohort occurred in abdominoplasties,’ the authors highlighted.

Haematoma: the most common complication

Hematomas accounted for the majority of complications (61.32 percent). Breast surgery contributed approximately one-third of these cases. Interestingly, the patients who developed haematomas had a median BMI of 22.8 kg/m2 and a shorter mean operative time (2.43 hours). This was in contrast to the higher-BMI, longer-duration cases more prone to VTE.

‘Although lower BMI and shorter operative times appeared to be statistically associated with higher haematoma rates, these findings are likely confounded by the short breast augmentation cases, which had the highest haematoma rates overall,’ said the authors.

The analysis, including a breast- specific subanalysis, discussed contrasting effects of BMI, operative time and combined procedures on the incidence of VTE and haematoma, highlighting a complex interplay of risk factors in the surgical setting.

While elevated BMI is a known risk factor for VTE, its relationship with haematoma formation is less clear. The authors note some studies suggest higher BMI may have a protective effect against bleeding complications, potentially due to procoagulant mechanisms linked to adipose tissue, such as increased thrombin generation and reduced fibrinolysis.

‘These pathways might explain the multifaceted relationship between VTEs and haematoma risks, representing opposite ends of the bleeding and coagulation spectrum,’ the authors write. ‘The study underscores the complexity of this association, as prolonged immobility during lengthy operations may elevate VTE risk. Conversely, longer operating times may signify more time dedicated to achieving haemostasis. Striking a delicate balance between these factors becomes paramount in optimising patient outcomes.’

Face-related procedures had the lowest overall complication rate, while body surgeries, especially those involving abdominoplasty, showed the highest incidence of serious complications such as VTE.

Venous thromboembolism: rare but serious

VTE events were infrequent – 17 cases across the entire cohort (0.04 percent) – yet concentrated in a high-risk patient profile. Of the VTEs recorded, 88.2 percent followed abdominoplasty, and 99.3 percent involved a combined procedure.

The authors found that VTE patients had a median BMI of 28.75 kg/m2, and median operative time of 4.86 hours. The majority had also received a lipoaspirate volume exceeding 3 litres. The triad of elevated BMI, prolonged surgical duration and high-volume liposuction emerged as the clearest composite risk signal.

Pre-operative patient optimisation

The study advocates for an optimisation framework tailored for surgical patients in the outpatient setting. Given the clear association between elevated BMI and increased complication risk – particularly in combined body procedures – the authors propose that preoperative BMI reduction may improve the safety profile of outpatient surgery.

In high-risk scenarios such as ‘mummy makeover’ combinations, encouraging weight loss prior to surgery or reconsidering the timing and staging of procedures may help balance patient goals with surgical safety. The authors suggest that tailored strategies, including reconsidering the simultaneous combination of procedures and extended postoperative monitoring, may be appropriate where BMI reduction is not achievable.

Postoperative care: who needs extra monitoring?

While this study does not offer specific guidance regarding the length and setting of monitoring, the authors agree: ‘When dealing with patients with BMIs exceeding 26 kg/m2, operative times over 3 hours, lipoaspirate volumes above 3 liters, and those undergoing combined procedures, surgeons should consider monitoring for at least several hours with qualified personnel.’

In the authors’ own practice, they operate an observation unit with postoperative nursing supervision and monitoring. ‘This allows us to monitor for signs of haematoma or bleeding and assist patients with postoperative pulmonary exercises and early ambulation. It also allows us, when deemed necessary, to initiate VTE chemoprophylaxis while monitoring patients for bleeding or haematoma (management of haematomas is determined by their size and by the stability of the patient),’ they share.

The authors conclude: ‘Outpatient plastic surgery can be performed in a consistent and safe manner with proper preoperative evaluation and patient optimisation.

‘Postoperative monitoring should be considered for high-risk patients, particularly those with a BMI exceeding 26 kg/m2, operative times surpassing 3 hours, lipoaspirate volumes greater than 3 litres and those undergoing combined procedures – with a particular emphasis on cases involving abdominoplasty.’

As Australia refines its regulatory and clinical frameworks around cosmetic procedures, the findings from this large-scale US study serve as a valuable resource for evidence- based decision-making.

For practitioners, the study affirms what many already practice: rigorous patient selection, appropriate procedural planning and commitment to safety protocols can keep complication rates exceptionally low. For regulators, it underscores the importance of accreditation and measurable thresholds in supporting high-quality, accountable care.

* Rohrich RN, Brown T, Brown S, Burns J, Jejurikar S, Meade R, Rohrich RJ. Three Decades of Outpatient Plastic Surgery Safety: A Review of 42,720 Consecutive Cases. Plast Reconstr Surg. 2025 Jul 1;156(1):49-61.

Identifying the key risk factors

The study identified three primary contributors to increased complication risk:

  1. Elevated BMI
  2. Longer operative duration
  3. Combined procedures

The authors note, ‘Patients who experienced a venous thromboembolism or an inpatient transfer had a higher body mass index, had a longer operative duration and were more likely to have undergone combined procedures.’

Identifying the risk thresholds

  • For VTE: BMI > 25.96 kg/m2 Operative time > 2.95 hours Lipoaspirate volume > 3025 mL
  • For inpatient transfer: BMI > 25.96 kg/m2 Operative time > 4.08 hours Lipoaspirate volume > 2900 mL
Aimée Rodrigues
Aimee is a highly respected health and beauty editor with in-depth experience in aesthetic medicine, health, beauty and wellness since 2006. Throughout her career, she has interviewed leading plastic surgeons, cosmetic doctors and influential figures in the beauty and lifestyle industries. Known for her ability to translate complex medical topics into accessible and engaging content, Aimee’s work aims to inform and empower readers on the latest in health and wellness advancements.
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