MicroFill and MacroFill from Medtel signify the latest in harvesting, treating and reinjecting small and large volumes of fat.
Medtel has conquered the fat harvesting paradigm. With solutions for small and large volume fat transfer, the MicroFill and MacroFill signify the latest technologies in the treatment and reinjection of fat, providing superior results in lipomodelling and lipofilling.
MacroFill is a closed circuit system for the harvesting, treatment and reinjection of large volumes of fat.
It is suitable for all indications requiring lipomodelling and can treat from 100 to 1400cc of adipose tissue in a single operation. As opposed to other systems, MacroFill delivers micro fat lobules, increasing cell survival and graft harvest rates.
A clinical study, conducted by Belgium plastic surgeon Dr Marc Nelissen, examined the MacroFill graft survival rates on 30 patients for breast corrections after DIEP surgery. He found a survival rate of greater that 75 percent at six months after transplantation.
Three major factors contribute to the MacroFill graft survival results: the controlled vacuum system; the multi- hold lipoaspiration cannulas; and the atraumatic washing protocol.
Control of negative pressure is essential during liposuction.
Several studies have shown that high negative pressure during liposuction is harmful to adipocytes, resulting in cell death, increased graft reabsorption and oil release. For example, an article by Herold C, et al. (2012) published in the Journal of Plastic, Reconstructive and Aesthetic Surgery states: “A negative pressure of 760 mmHg has been shown to provoke an adipocyte injury rate of 90 percent.” The report goes on to advise using gentle manual syringe liposuction for the best results.
Similarly, in the article entitled “Lipofilling: Critical points for successful fat grafting” by Girard, Hivernaud, Gauthier, Festy and Roche (2014), the authors explain that a high negative pressure of 50ml can generate more than a two- fold increase of oil, contributing to fat necrosis.
According to Medtel, optimum liposuction results are achieved using a low vacuum at less than 0.5 bar. Their products allow the practitioner to regulate negative pressure and preserve cell survival using Spinfill ‘vacuum controlled’ 60cc syringes.
Tests performed with a Spinfill syringe and 3.5mm by 200mm cannula resulted in 0.45 bar vacuum, which is within the optimum range (ie, under 0.5 bar).
The Medtel MacroFill uses multi-hole lipoaspiration cannulas to increase vascularisation of collected lobules and prevent fat necrosis.
Maintaining vascularisation is key in preventing fat necrosis, as a study by Ferraro G. A, et al. (2011) published in the journal of Aesthetic Plastic Surgery explains.
“A problem that limits the use and the success of fat graft is the lack of adequate donor-site vascularisation because many of the transplanted cells are mature adipocytes that do not have the capacity to replicate and their survival is linked to blood supply,” the authors state.
The hole size on the MacroFill cannulas are optimised to ensure the provision of micro fat lobules. The ‘micro’ sizes allows for high graft vascularisation, protecting against fat necrosis and boosting cell graft survival.
Washing protocol Washing the fat is critical in eliminating inflammatory molecules, cell death signals and local anaesthetics. Centrifugation eliminates infiltration liquid, allowing reinjection of a true volume of fat and maintaining physiological cell communication. The way the fat is processed will drastically affect the final product – influencing graft quality and durability.
“It is necessary to wash and centrifuge adipose tissue before reinjection in order to remove infiltration liquid and associated toxic molecules, which in the long term are deleterious for the graft,” states a report by Hoareau L, et al. (2013) entitled “Effect of centrifugation and washing on adipose graft viability: A new method to improve graft efficiency”.
“However, strong centrifugation is not recommended since it leads very quickly to great adipocyte death. Thus, soft centrifugation (400g /1 min), preceded by washings, seems to be the most appropriate protocol for the reinjection of adipose tissue,” the authors continue.
The Medtel fat harvesting system uses an atraumatic washing protocol, with short duration and low speed centrifugation. This is optimised to preserve cell and tissue survival.
The popularity of lipofilling for facial rejuvenation has grown drastically in the past decade.
“The main indication for lipostructure is facelift and profile correction involving cheekbones, lips, furrows around the nose, chin, jaw or localised atrophies,” Ferraro et al. (2011) states. “Because the volume of the lost soft tissue is often due to ageing of skin and subcutaneous tissues, lipostructure in these cases may represent an ideal solution.”
MicroFill is a closed lipoaspiration and lipofilling system designed to enhance the volume of sub- dermal areas, particularly in facial rejuvenation. As with the MacroFill system, it does this by delivering adipose microlobules to boost cell survival and graft harvest rates.
A clinical study examining MicroFill on 10 patients, conducted by plastic surgeon Dr Darina Krastinova in France, found a fat survival rate of more than 70 percent after six months in facial reconstruction. She also noted a significant improvement in skin texture and elasticity.
MicroFill uses low depression during aspiration to conserve cellular survival. The aspiration is performed with a multi-hole cannula to allow sampling and injection of very fine adipose lobules, which are easily vascularised.
Again, the washing and centrifugation protocol is atraumatic to preserve cell and tissue survival, and the MicroFill system employs fine cannulas to ensure a smooth and applicable sub-dermal reinjection.
For enquiries please visit www.medtelaesthetic.com.au or call 1300 668 140